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Proposals to Amend (No. 2) the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards 2008

3 Proposal to set an MRL for Cyprodinil

It is proposed that an MRL is set for cyprodinil when used as a fungicide for stonefruit (except cherries). It is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended by deleting the following entry:

Compound	CAS#	Residue definition	Food	Maximum Residue Limit (mg/kg)
Cyprodinil	121552-61-2	Cyprodinil	Nectarines Peaches	0.02 0.02

As a replacement for the deleted entry, it is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended to include:

Compound	CAS#	Residue definition	Food	Maximum Residue Limit (mg/kg)
Cyprodinil	121552-61-2	Cyprodinil	Stonefruit (except cherries)	0.02*

NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.

The final entry for cyprodinil in Schedule One of the NZ (MRL) Food Standards 2008 will therefore read:

Compound	CAS#	Residue definition	Food	Maximum Residue Limit (mg/kg)
Cyprodinil	121552-61-2	Cyprodinil	Grapes Pome fruits Stonefruit (except cherries)	0.2 0.01 0.02*

NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.

Amendment Rationale

The proposed MRL represents a new use pattern in New Zealand for the active ingredient cyprodinil. The proposed MRLs will manage the new uses of cyprodinil as a fungicide on stonefruit to the application rates and withholding periods that are approved good agricultural practice (GAP) in New Zealand (see below).

Chemical Information

Common name of compound	Cyprodinil
Use of compound	Fungicide
Chemical Abstract Services (CAS) Registry number	121552-61-2
Type of compound	Pyrimidine
Administration method	Spray

Good Agricultural Practice

Cyprodinil is proposed for use as a fungicide for apricots. Application may be up to 4 times until 90% petal fall, at 15gai/100L with a withholding period of: do not apply after 90% petal fall.

Residues Information

Residue data for apricots supports an MRL of 0.02mg/kg at approximately 76 days after the last treatment. A limit of quantification MRL of 0.02mg/kg is therefore proposed to support GAP. The MRL is proposed to be combined with current MRLs for peaches and nectarines to establish a crop group MRL of 0.02mg/kg for stonefruit (except cherries).

Animal Transfer: Stonefruit are not primary animal feeds, therefore no animal commodity MRLs are proposed.

Dietary Risk Assessment

Acceptable Daily Intake (ADI)

0.027mg/kg bw/day

The potential daily exposure via food (PDE_(food)) is used for dietary intake calculation where a value has been set. An appropriate acceptable daily intake (ADI) is used in the absence of a PDE_(food).

The chronic dietary exposure to cyprodinil is estimated by the National Estimated Dietary Intake (NEDI) calculation encompassing all registered uses of the chemical and food consumption data based upon the 1997 National Nutritional Survey for adults and the 1995 National Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with Guidelines for predicting dietary intake of pesticide residues (revised) [World Health Organization, 1997].

The NEDI for cyprodinil is equivalent to 0.3% of the ADI. It is therefore concluded that the chronic dietary exposure is small and the risk is acceptable.

Toxicological / Public Health Assessment

It has been determined that the use of cyprodinil as a fungicide for use on stonefruit, according to the GAP specified above, is very unlikely to pose any health risks from consumption of the harvested commodity.

Other International MRLs

To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and Phytosanitary Measures the proposed MRL will be notified to the World Trade Organization. Any country may choose to comment if they believe the proposed MRL represents a barrier to their trade.