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Proposals to Amend (No. 2) the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards 2008

10 Proposal to set an MRL for Pyraclostrobin

It is proposed that an MRL is set for pyraclostrobin when used as a fungicide for grapes. It is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended to include:

Compound

CAS#

Residue definition

Food

Maximum Residue Limit (mg/kg)

Pyraclostrobin

175013-18-0

Plant commodities:

Sum of:

Pyraclostrobin and its desmethoxy

metabolite

Expressed as:

Pyraclostrobin

Animal commodities:

Sum of:

Pyraclostrobin and metabolites

hydrolysed to: 1-(4-chloro-phenyl)-

1H-pyrazol- 3-ol

Expressed as:

Pyraclostrobin

Grapes

3

The final entry for pyraclostrobin in Schedule One of the NZ (MRL) Food Standards 2008 will therefore read:

Compound

CAS#

Residue definition

Food

Maximum Residue Limit (mg/kg)

Pyraclostrobin

175013-18-0

Plant commodities:

Sum of:

Pyraclostrobin and its desmethoxy

metabolite

Expressed as:

Pyraclostrobin

Animal commodities:

Sum of:

Pyraclostrobin and metabolites

hydrolysed to: 1-(4-chloro-phenyl)-

1H-pyrazol- 3-ol

Expressed as:

Pyraclostrobin

Apples

Barley Grapes

Mammalian fat

Mammalian kidney

Mammalian liver

Mammalian meat

Milk

Pears

Wheat

0.02(*)

0.02(*)

3

0.02(*)

0.02(*)

0.02(*)

0.02(*)

0.02(*)

0.02(*)

0.02(*)

NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.

Amendment Rationale

The proposed MRL represents a new use pattern in New Zealand for the active ingredient pyraclostrobin. The proposed MRL will manage the new uses of pyraclostrobin as a fungicide on grapes to the application rates and withholding periods that are approved good agricultural practice (GAP) in New Zealand (see below).

Chemical Information

Common name of compound

Pyraclostrobin

Use of compound

Fungicide

Chemical Abstract Services (CAS) Registry number

175013-18-0

Type of compound

Strobilurin

Administration method

Spray

Good Agricultural Practice

Pyraclostrobin is proposed for use as a fungicide for grapes. Application may be throughout pre-flowering to pre-harvest, at rate of 192gai/ha with a withholding period of 28 days.

Residues Information

Residue data for grapes supports an MRL of 3 mg/kg at 28 days after the last treatment. An MRL of 3mg/kg is therefore proposed to support GAP.

Animal Transfer: Grape pomace and vineyard waste may be fed to animals, however given the expected consumption level of pyraclostrobin in these commodities it would not be expected that residues would exceed the current animal commodity MRLs.

Dietary Risk Assessment

Acceptable Daily Intake (ADI)

0.03 mg/kg bw/day

The potential daily exposure via food (PDE(food)) is used for dietary intake calculation where a value has been set. An appropriate acceptable daily intake (ADI) is used in the absence of a PDE(food).

The chronic dietary exposure to pyraclostrobin is estimated by the National Estimated Dietary Intake (NEDI) calculation encompassing all registered uses of the chemical and food consumption data based upon the 1997 National Nutritional Survey for adults and the 1995 National Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with Guidelines for predicting dietary intake of pesticide residues (revised) [World Health Organization, 1997].

The NEDI for pyraclostrobin is equivalent to 1% of the ADI. It is therefore concluded that the chronic dietary exposure is small and the risk is acceptable.

Toxicological / Public Health Assessment

It has been determined that the use of pyraclostrobin as a fungicide for use on grapes, according to the GAP specified above, is very unlikely to pose any health risks from consumption of the harvested commodity.

Other International MRLs

To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and Phytosanitary Measures the proposed MRL will be notified to the World Trade Organization. Any country may choose to comment if they believe the proposed MRL represents a barrier to their trade.

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