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Proposals to Amend the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards 2008

3 Proposal to set an MRL for Cyprodinil

It is proposed that an MRL is set for cyprodinil when used as a fungicide for bulb onions. It is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended to include:

Compound

CAS#

Residue definition

Food

Maximum Residue Limit (mg/kg)

Cyprodinil

121552-61-2

Cyprodinil

Bulb onions

0.01*

NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.

The final entry for cyprodinil in Schedule One of the NZ (MRL) Food Standards 2008 will therefore read:

Compound

CAS#

Residue definition

Food

Maximum Residue Limit (mg/kg)

Cyprodinil

121552-61-2

Cyprodinil

Bulb onions

Grapes

Pome fruits

Stonefruit (except cherries)

Strawberries

0.01*

0.2

0.01

0.02*

1

NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.

Amendment Rationale

The proposed MRL represents a new use patterns in New Zealand for the active ingredient Cyprodinil. The proposed MRL will manage the new use of cyprodinil as a fungicide on bulb onions to the application rates and withholding periods that are approved good agricultural practice in New Zealand

Chemical Information

Common name of compound

Cyprodinil

Use of compound

Fungicide

Chemical Abstract Services (CAS) Registry number

121552-61-2

Type of compound

Pyrimidine

Administration method

Spray

Good Agricultural Practice

Cyprodinil is proposed for use as a fungicide for bulb onions. Application may be up to 2 times per season, at 300gai/ha with a withholding period of 7 days.

Residues Information

Residue data for bulb onions supports a limit of quantification MRL of 0.01mg/kg at 7 days after the last treatment. An MRL of 0.01mg/kg is therefore proposed to support GAP.

Animal Transfer

No residues are expected in treated onions thus no animal transfer will occur.

Dietary Risk Assessment

Acceptable Daily Intake (ADI)

0.027mg/kg bw/day

The potential daily exposure via food (PDE(food)) is used for dietary intake calculation where a value has been set. An appropriate acceptable daily intake (ADI) is used in the absence of a PDE(food).

The chronic dietary exposure to cyprodinil is estimated by the National Estimated Dietary Intake (NEDI) calculation encompassing all registered uses of the chemical and food consumption data based upon the 1997 National Nutritional Survey for adults and the 1995 National Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with Guidelines for predicting dietary intake of pesticide residues (revised) [World Health Organisation, 1997].

The NEDI for cyprodinil is equivalent to 0.3% of the ADI. It is therefore concluded that the chronic dietary exposure is small and the risk is acceptable.

Toxicological / Public Health Assessment

It has been determined that the use of cyprodinil as a fungicide for use on bulb onions, according to the good agricultural practice specified above, is very unlikely to pose any health risks from consumption of the harvested commodity

Other International MRLs

To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and Phytosanitary Measures the proposed MRLs will be notified to the World Trade Organization. Any country may choose to comment if they believe the proposed MRLs represent a barrier to their trade.

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