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Proposals to Amend the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards 2008
3 Proposal to set an MRL for Cyprodinil
It is proposed that an MRL is set for cyprodinil when used as a fungicide for bulb onions. It is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended to include:
Compound |
CAS# |
Residue definition |
Food |
Maximum Residue Limit (mg/kg) |
Cyprodinil |
121552-61-2 |
Cyprodinil |
Bulb onions |
0.01* |
NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.
The final entry for cyprodinil in Schedule One of the NZ (MRL) Food Standards 2008 will therefore read:
Compound |
CAS# |
Residue definition |
Food |
Maximum Residue Limit (mg/kg) |
Cyprodinil |
121552-61-2 |
Cyprodinil |
Bulb onions Grapes Pome fruits Stonefruit (except cherries) Strawberries |
0.01* 0.2 0.01 0.02* 1 |
NOTE: (*) indicates that the maximum residue limit has been set at or about the limit of analytical quantification.
Amendment Rationale
The proposed MRL represents a new use patterns in New Zealand for the active ingredient Cyprodinil. The proposed MRL will manage the new use of cyprodinil as a fungicide on bulb onions to the application rates and withholding periods that are approved good agricultural practice in New Zealand
Chemical Information
Common name of compound |
Cyprodinil |
Use of compound |
Fungicide |
Chemical Abstract Services (CAS) Registry number |
121552-61-2 |
Type of compound |
Pyrimidine |
Administration method |
Spray |
Good Agricultural Practice
Cyprodinil is proposed for use as a fungicide for bulb onions. Application may be up to 2 times per season, at 300gai/ha with a withholding period of 7 days.
Residues Information
Residue data for bulb onions supports a limit of quantification MRL of 0.01mg/kg at 7 days after the last treatment. An MRL of 0.01mg/kg is therefore proposed to support GAP.
Animal Transfer
No residues are expected in treated onions thus no animal transfer will occur.
Dietary Risk Assessment
Acceptable Daily Intake (ADI) |
0.027mg/kg bw/day |
The potential daily exposure via food (PDE(food)) is used for dietary intake calculation where a value has been set. An appropriate acceptable daily intake (ADI) is used in the absence of a PDE(food).
The chronic dietary exposure to cyprodinil is estimated by the National Estimated Dietary Intake (NEDI) calculation encompassing all registered uses of the chemical and food consumption data based upon the 1997 National Nutritional Survey for adults and the 1995 National Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with Guidelines for predicting dietary intake of pesticide residues (revised) [World Health Organisation, 1997].
The NEDI for cyprodinil is equivalent to 0.3% of the ADI. It is therefore concluded that the chronic dietary exposure is small and the risk is acceptable.
Toxicological / Public Health Assessment
It has been determined that the use of cyprodinil as a fungicide for use on bulb onions, according to the good agricultural practice specified above, is very unlikely to pose any health risks from consumption of the harvested commodity
Other International MRLs
To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and Phytosanitary Measures the proposed MRLs will be notified to the World Trade Organization. Any country may choose to comment if they believe the proposed MRLs represent a barrier to their trade.
New Zealand Food Safety Authority
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