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Proposals to Amend the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards 2008
4 Proposal to set an MRL for Cyprodinil
It is proposed that an MRL is set for cyprodinil when used as a fungicide for strawberries. It is proposed that Schedule One of the NZ (MRL) Food Standards 2008 be amended to include the following entry:
Compound |
CAS# |
Residue definition |
Food |
Maximum Residue Limit (mg/kg) |
Cyprodinil |
121552-61-2 |
Cyprodinil |
Strawberries |
1 |
The final entry for cyprodinil in Schedule One of the NZ (MRL) Food Standards 2008 will therefore read:
Compound |
CAS# |
Residue definition |
Food |
Maximum Residue Limit (mg/kg) |
Cyprodinil |
121552-61-2 |
Cyprodinil |
Grapes Nectarines Peaches Pome fruits Strawberries |
0.2 0.02 0.02 0.01 1 |
Amendment Rationale
The proposed MRL represents a new use pattern in New Zealand for the active ingredient cyprodinil. The proposed MRL will manage the new use of cyprodinil as a fungicide on strawberries to the application rates and withholding periods that are approved good agricultural practice (GAP) in New Zealand (see below).
Chemical Information
Common name of compound |
Cyprodinil |
Use of compound |
Fungicide |
Chemical Abstract Services (CAS) Registry number |
121552-61-2 |
Type of compound |
Pyrimidine |
Administration method |
Spray |
Good Agricultural Practice
Cyprodinil is proposed for use as a fungicide for strawberries. Application may be 2-3 times at 7-14 day intervals after flowering, at 300gai/ha with a withholding period of 3 days.
Residues Information
Residue data for strawberries support an MRL of 1mg/kg at 3 days after the last treatment. An MRL of 1mg/kg is therefore proposed to support GAP.
Animal Transfer
Strawberries are not considered an animal feed commodity. Animal derived food product limits are therefore not proposed.
Dietary Risk Assessment
Acceptable Daily Intake (ADI) |
0.027mg/kg bw/day |
The potential daily exposure via food (PDE(food)) is used for dietary intake calculation where a value has been set. An appropriate acceptable daily intake (ADI) is used in the absence of a PDE(food).
The chronic dietary exposure to cyprodinil is estimated by the National Estimated Dietary Intake (NEDI) calculation encompassing all registered uses of the chemical and food consumption data based upon the 1997 National Nutritional Survey for adults and the 1995 National Nutrition Survey of Australia, for children. The NEDI calculation is made in accordance with Guidelines for predicting dietary intake of pesticide residues (revised) [World Health Organisation, 1997].
The NEDI for cyprodinil is equivalent to 0.3% of the ADI. It is therefore concluded that the chronic dietary exposure is small and the risk is acceptable.
Toxicological / Public Health Assessment
It has been determined that the use of cyprodinil as a fungicide for use on strawberries, according to the GAP specified above, is very unlikely to pose any health risks from consumption of the harvested commodity.
Other International MRLs
Compound |
Food |
Maximum Residue Limit (mg/kg) |
The Netherlands |
||
Cyprodinil |
Strawberries |
2 |
To meet New Zealand’s obligations under the Agreement on the Application of Sanitary and Phytosanitary Measures the proposed MRL will be notified to the World Trade Organization. Any country may choose to comment if they believe the proposed MRL represents a barrier to their trade.
New Zealand Food Safety Authority
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